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Hand-coded by chemists and engineered by computer scientists, this synthetic planning tool draws from a profound chemical abstracts database of advanced organic synthesis rules and algorithms. Computer-aided synthesis allows you to rapidly generate synthetic routes to identified targets.

Based on years of development as Chematica, then further enhancement as SYNTHIA™, this software now enables chemists to easily navigate through viable pathways that can be executed at the bench.

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Experience Our Powerful SYNTHIA™ Retrosynthesis Software with A Free Individual Trial

In laboratory validation, SYNTHIA™ Lite retrosynthesis software found robust and reliable pathways that reduce synthetic steps, increase yields, and decrease costs for both known and novel targets.

Benefits of SYNTHIA™ Lite:

  • Cloud-Based Application.
  • 30 Day Free Trial for up to 5 Target Molecules.
  • Individual license of SYNTHIA™ with the power of SYNTHIA™ Enterprise.
  • Easy Upgrade to the Enterprise version of SYNTHIA™ retrosynthesis software.

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Accelerate synthesis design with SYNTHIA™ Retrosynthesis Software

Chemical synthesis is not just tricky – it’s risky.

From supply chain shortages to regulatory restrictions to safety considerations— reducing risk is a top priority.

SYNTHIA™ retrosynthesis software reduces risk by identifying multiple, shorter, more robust pathways, which saves time and reduces costs.

Using hand-coded rules and powerful AI developed over 15 years, this decision support tool has become the strategic partner of organic chemists in laboratories across pharma, biotechnology, chemical industry and academia.

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Reducing Risk and Improving Synthesis Outcomes in Drug Discovery with SYNTHIA™ Retrosynthesis Software

Today’s synthesis planning for drug discovery relies on connecting the wisdom and practical expertise of an experienced organic chemist with the automation and advanced algorithms found in modern retrosynthesis software. This five-part series, sponsored by MilliporeSigma, will enable you to pioneer a pathway to more efficient, sustainable drug discovery. The articles featured here emphasize the importance of retrosynthesis software to help mitigate risk and augment your lab staff’s expertise, offer tips to implement‚ greener‘ chemistry, outline the steps to scale-up a synthesis reaction, and more.

Table Of Contents

  • Overcoming Key Challenges in Drug Discovery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
  • Using High-Throughput Screening to Rapidly Identify Targets. . . . . . . . . . . . . . . . 6
  • Three Ways to Improve the Sustainability of Your Lab’s Chemical Synthesis . .9
  • How to Scale Up a New Synthesis Reaction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
  • Computer-Aided Synthesis Reduces Complexity and Accelerates Novel Chemical Discoveries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
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Self-Awareness: The Key to Becoming a Complete Leader

Leaders lead, managers manage, supervisors supervise.

More Importantly, they lead others, manage others, and supervise others.

But when was the last time they supervised or managed themselves? Is that even an area of concern for them? Or have they grown so accustomed to observing others that they had forgotten that the fundamental trait of being an effective leader is to be aware of their own behaviors?

Are they aware of how their behaviors are affecting team cohesion, productivity, engagement and more importantly, organizational goals?

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Developing a Leadership Capability Framework to Increase Employee Engagement, Retention and Productivity

Enterprises are facing multiple challenges when it comes to both employee engagement/retention and productivity. The current historical low unemployment rates mean that it’s difficult for all employers to find new, and quality, talent. Employees, understanding that they can move if dissatisfied with the leadership and/or their functional work, are doing so: one third of Australian workers are considering quitting their jobs as the “great resignation” continues to disrupt organisations in all sectors.

Meanwhile, another 30 per cent of workers are actively participating in quiet quitting. Quiet quitting describes employees that refuse to work beyond the minimum required of their job – this includes overtime and taking on additional responsibilities. Should an organisation become too filled with “quiet quitters”, the overall productivity and ability for the organisation to be nimble will be compromised.

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How To Conduct 360° Leadership Feedback Survey Debriefs

There are a few key points to note when preparing to deliver a 360 debrief:

  • The goal is to identify a maximum of four development areas that will improve leadership capability.
  • Make your feedback relevant to the individual’s role responsibilities, especially strategy, people, innovation & organizational knowledge.
  • Continually reinforce that the 360 survey measures perceptions and what you are looking for is differences in the perceptions of the respondents.

We strongly recommend printing off the report and following our structured process as outlined in this guide.

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Macabacus for Lenders

Build better financial models and presentations faster with the most comprehensive suite of productivity and brand compliance solutions available for Microsoft Office.

Macabacus helps teams perform complex analysis quickly, standardize presentations, and manage brand compliant assets.

Discover our features:

  • Financial modeling.
  • Link-to-Excel.
  • Content management.

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Macabacus Live Demo + Q&A

Ready to Save 100s of Hours Annually?

Find out how you and your team could speed up financial modeling and presentation tasks.

  • Accelerate financial modeling with 100+ Excel shortcuts.
  • Create precise models with formula auditing.
  • Link Excel data to PowerPoint images & charts.

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Elevating Physical Security and Cybersecurity with Machine Vision AI

AI-powered machine vision has the transformative potential to significantly bolster physical security and cybersecurity across critical industries. This whitepaper delves into the strategic integration of cutting-edge technology with physical and cyber security practices to enhance protection measures. By exploring real-world applications and future trends, this document outlines how AI-powered machine vision empowers data integrity, operational resilience, risk mitigation, and enterprise fortitude.

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The Future of Physical Security: Harnessing Artificial Intelligence for Proactive Protection

In an increasingly interconnected world, the realm of physical security is undergoing a transformation driven by rapid technological advancements. The integration of video analytics with traditional security measures is shaping the future of safeguarding people, property, and assets. This evolution is paving the way for more efficient, proactive, and intelligent security solutions that transcend conventional methods. In this article, we’ll delve into the convergence of physical security and video analytics, exploring how this synergy is redefining the way we approach safety and protection.

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Wallet Solutions

Onboard your users with our easy-to-implement wallet solutions. Choose our Wallet API to take full control of the UX, or the Wallet Widget - where we take care of security and compliance.

Venly Wallet allows your users to interact with Web3 familiarly, while we take care of the security & complexity. Integrate our widget in minutes or go for our API solution to get total freedom on UX and asset management.

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NFT Solutions

Build & scale your project with our comprehensive set of Web3 tools. We provide wallet services, marketplace solutions, NFT tools, and more.

To realize our vision of bringing blockchain to the mainstream, we offer NFT tools for anyone to access Web3. Looking to make and sell NFTs? This is a great place to start.

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Gaming Solutions

Effortlessly onboard players into the world of Web3 and build a thriving community around your game. Boost engagement and create new monetization opportunities by incorporating NFTs into gameplay.

Our Web3 Gaming Toolkit is simple for you and your users. You'll launch your game ahead of schedule, while options like social login will eliminate friction for your players.

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E-Commerce Solutions

Engage your customers with exclusive NFT collections, gated virtual experiences, and tokenized “phygital” assets. The opportunities are endless and you can do it all with one app.

NFTs are changing e-commerce as we know it. Don’t get left behind. Community building, digital twins, gated content, customer profiling - see what you can do with tokens.

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