Academic Promotional Pricing Available Now

Hand-coded by chemists and engineered by computer scientists, this synthetic planning tool draws from a profound chemical abstracts database of advanced organic synthesis rules and algorithms. Computer-aided synthesis allows you to rapidly generate synthetic routes to identified targets.

Based on years of development as Chematica, then further enhancement as SYNTHIA™, this software now enables chemists to easily navigate through viable pathways that can be executed at the bench.

View Now

Experience Our Powerful SYNTHIA™ Retrosynthesis Software with A Free Individual Trial

In laboratory validation, SYNTHIA™ Lite retrosynthesis software found robust and reliable pathways that reduce synthetic steps, increase yields, and decrease costs for both known and novel targets.

Benefits of SYNTHIA™ Lite:

  • Cloud-Based Application.
  • 30 Day Free Trial for up to 5 Target Molecules.
  • Individual license of SYNTHIA™ with the power of SYNTHIA™ Enterprise.
  • Easy Upgrade to the Enterprise version of SYNTHIA™ retrosynthesis software.

View Now

Accelerate synthesis design with SYNTHIA™ Retrosynthesis Software

Chemical synthesis is not just tricky – it’s risky.

From supply chain shortages to regulatory restrictions to safety considerations— reducing risk is a top priority.

SYNTHIA™ retrosynthesis software reduces risk by identifying multiple, shorter, more robust pathways, which saves time and reduces costs.

Using hand-coded rules and powerful AI developed over 15 years, this decision support tool has become the strategic partner of organic chemists in laboratories across pharma, biotechnology, chemical industry and academia.

View Now

Reducing Risk and Improving Synthesis Outcomes in Drug Discovery with SYNTHIA™ Retrosynthesis Software

Today’s synthesis planning for drug discovery relies on connecting the wisdom and practical expertise of an experienced organic chemist with the automation and advanced algorithms found in modern retrosynthesis software. This five-part series, sponsored by MilliporeSigma, will enable you to pioneer a pathway to more efficient, sustainable drug discovery. The articles featured here emphasize the importance of retrosynthesis software to help mitigate risk and augment your lab staff’s expertise, offer tips to implement‚ greener‘ chemistry, outline the steps to scale-up a synthesis reaction, and more.

Table Of Contents

  • Overcoming Key Challenges in Drug Discovery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
  • Using High-Throughput Screening to Rapidly Identify Targets. . . . . . . . . . . . . . . . 6
  • Three Ways to Improve the Sustainability of Your Lab’s Chemical Synthesis . .9
  • How to Scale Up a New Synthesis Reaction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
  • Computer-Aided Synthesis Reduces Complexity and Accelerates Novel Chemical Discoveries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Get Whitepaper

Protecting Your Intellectual Property and Expanding Your Markets

Enterprise connectivity represents a massive opportunity for both machine builders and their customers.

But the risks associated with having a complex, interconnected system – from cybercriminals and competitors – are growing. Almost one in two companies has experienced illicit copying of entire machines. Cyberattacks can cause damage to physical assets, workers or products.

Fundamental to today’s production environment is the ability to provide secure, remote access for end customers, improve productivity and safety, protect critical production data from internal and external threats, while keeping intellectual property equally secure.

View Now

Scalable Secure Remote Access Solutions for OEMs

Secure remote access to production assets, data and applications, along with the latest collaboration tools, provides plant and sites with the ability to apply the right skills and resources at the right time, independent of their physical location. OEMs are looking to reduce costs, add more value to their Industrial Automation and Control Systems (IACS) customers and differentiate themselves from their competitors. This paper outlines the means to enable secure remote access to plant or site-based applications and data and can be used as guidance for OEMs to collaborate with their customers when designing a secure remote access solution.

Get Whitepaper

Realizing Digital Value: Three Opportunity Areas for OEMs

Success as an OEM has always hinged on the ability to design and deploy machines in ways that yield rapid time to value, no matter the challenges that may be involved.

Industry challenges, both perennial and new, are likely here to stay.

What’s different now is the technology landscape and opportunities it presents for OEMs to not only maximize efficiency from within, but also to differentiate themselves and strengthen their position in the marketplace.

View Now

Protecting Your Intellectual Property and Expanding Your Markets

Enterprise connectivity represents a massive opportunity for both machine builders and their customers.

But the risks associated with having a complex, interconnected system – from cybercriminals and competitors – are growing. Almost one in two companies has experienced illicit copying of entire machines. Cyberattacks can cause damage to physical assets, workers or products.

Fundamental to today’s production environment is the ability to provide secure, remote access for end customers, improve productivity and safety, protect critical production data from internal and external threats, while keeping intellectual property equally secure.

View Now

Scalable Secure Remote Access Solutions for OEMs

Secure remote access to production assets, data and applications, along with the latest collaboration tools, provides plant and sites with the ability to apply the right skills and resources at the right time, independent of their physical location. OEMs are looking to reduce costs, add more value to their Industrial Automation and Control Systems (IACS) customers and differentiate themselves from their competitors. This paper outlines the means to enable secure remote access to plant or site-based applications and data and can be used as guidance for OEMs to collaborate with their customers when designing a secure remote access solution.

Get Whitepaper

Realizing Digital Value: Three Opportunity Areas for OEMs

Success as an OEM has always hinged on the ability to design and deploy machines in ways that yield rapid time to value, no matter the challenges that may be involved.

Industry challenges, both perennial and new, are likely here to stay.

What’s different now is the technology landscape and opportunities it presents for OEMs to not only maximize efficiency from within, but also to differentiate themselves and strengthen their position in the marketplace.

View Now

State of Smart Manufacturing Report

Every day, we navigate a complex landscape: aiming for increased profitable growth without sacrificing quality; building greater resiliency and agility; stretching to make operations more sustainable; and tackling workforce and supply chain challenges simultaneously.

What can we learn from our common struggles? And how can we leverage global trends to reach our own goals? This research spotlights one common thread: the need for technology to mitigate risks, open up new opportunities, and remain competitive.

Complete the form to download the State of Smart Manufacturing Report now!

View Now

Protecting Your Intellectual Property and Expanding Your Markets

Enterprise connectivity represents a massive opportunity for both machine builders and their customers.

But the risks associated with having a complex, interconnected system – from cybercriminals and competitors – are growing. Almost one in two companies has experienced illicit copying of entire machines. Cyberattacks can cause damage to physical assets, workers or products.

Fundamental to today’s production environment is the ability to provide secure, remote access for end customers, improve productivity and safety, protect critical production data from internal and external threats, while keeping intellectual property equally secure.

View Now

Scalable Secure Remote Access Solutions for OEMs

Secure remote access to production assets, data and applications, along with the latest collaboration tools, provides plant and sites with the ability to apply the right skills and resources at the right time, independent of their physical location. OEMs are looking to reduce costs, add more value to their Industrial Automation and Control Systems (IACS) customers and differentiate themselves from their competitors. This paper outlines the means to enable secure remote access to plant or site-based applications and data and can be used as guidance for OEMs to collaborate with their customers when designing a secure remote access solution.

Get Whitepaper

Realizing Digital Value: Three Opportunity Areas for OEMs

Success as an OEM has always hinged on the ability to design and deploy machines in ways that yield rapid time to value, no matter the challenges that may be involved.

Industry challenges, both perennial and new, are likely here to stay.

What’s different now is the technology landscape and opportunities it presents for OEMs to not only maximize efficiency from within, but also to differentiate themselves and strengthen their position in the marketplace.

View Now

Protecting Your Intellectual Property and Expanding Your Markets

Enterprise connectivity represents a massive opportunity for both machine builders and their customers.

But the risks associated with having a complex, interconnected system – from cybercriminals and competitors – are growing. Almost one in two companies has experienced illicit copying of entire machines. Cyberattacks can cause damage to physical assets, workers or products.

Fundamental to today’s production environment is the ability to provide secure, remote access for end customers, improve productivity and safety, protect critical production data from internal and external threats, while keeping intellectual property equally secure.

View Now